Overview
Protecting your puppy against life-threatening diseases is one of the most important things you need to do. While your puppy is growing up big and strong, vaccines keep them safe from serious and often life-threatening diseases like parvovirus, distemper, leptospirosis, and infectious canine hepatitis.
Puppy vaccinations are split into two categories, core and non-core. Core vaccinations are vaccines that are recommended for all dogs. Non-core vaccinations are additional vaccines that protect against certain diseases your dog may or may not be at risk of. All core vaccines and boosters are included in Pet Health Club membership.
First vaccination: six to 10 weeks old
Your puppy's first set of vaccinations is usually given when they're between six and 10 weeks old. This protects them against:
Parvovirus is a highly contagious virus causing severe vomiting, diarrhoea, and dehydration. It's particularly dangerous for young puppies.
Distemper is a serious virus that can cause fever, breathing problems, and long-term neurological issues.
Infectious canine hepatitis (ICH) affects the liver, kidneys, and eyes.
Leptospirosis is a bacterial infection that can damage vital organs like the kidneys and liver. It can also spread to humans.
Puppy vaccination schedule
Read more: Puppy vaccination FAQs
Second vaccination: 10 to 14 weeks old
The second vaccination is given between 10 and 14 weeks. This strengthens their protection against parvovirus, distemper, leptospirosis, and infectious hepatitis. These two injections are needed to build up full immunity. They'll also now receive their contagious cough (also known as kennel cough) vaccine.
At this time, your puppy will also be able to be given a rabies vaccine. This is only required if you are actively planning to take your puppy abroad — otherwise it isn't necessary.
Third vaccination (if needed): 16 to 26 weeks old
Many puppies may need a third injection, but some are fine with just two. Your vet will let you know if your puppy needs a third dose to give them the best protection. If they do need a third dose at this stage, it will be a single injection of the three-in-one (covering distemper, hepatitis, and parvovirus).
Boosters
Once your puppy is a year old, they'll need their first booster to keep their immunity strong. This booster covers:
Leptospirosis
Contagious cough (also called kennel cough)
They'll need to receive a booster protecting from these two illnesses every 12 months. Additionally, every third year, your dog will need a booster of the three-in-one, refreshing their protection against:
Parvovirus
Distemper
Infectious hepatitis
Keeping up with boosters helps maintain their protection throughout their life.
How do I keep puppy safe before they're fully vaccinated?
Until your puppy has had all their vaccinations, it's important to limit their exposure to places where they could pick up infections. Here are a few tips:
Avoid public places like parks or pavements where other dogs might have been.
Only let them socialise with dogs that are fully vaccinated.
If you need to take them out, carry them rather than letting them walk in risky areas.
Need more info on your puppy's vaccinations?
For expert advice on puppy vaccinations, get in touch with your local vet. And remember, your puppy's core vaccinations are fully covered in Pet Health Club membership.
Find your nearest vet using our find a vet page.
Join the club today
Get regular health checks, vaccinations, and more, all included in your plan.
Medically reviewed by Lizzie Youens, BSc(Hons) BVSc MRCVS
Published on 06/04/2023 • Reviewed on 26/04/2026